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Quick summary

Type of medicine

Topical Psoriasis Relief

Works by

Soothing Psoriasis Symptoms

Active Ingredient

Coal Tar

Effective within

Varies by Individual



Side effects

Skin Irritation, Sensitivity to Sunlight

Medication details


E45 Psoriasis Cream 50ml is a specialized topical treatment designed to provide relief and management for individuals with psoriasis, a chronic skin condition characterized by red, scaly patches that can be itchy, painful, and aesthetically challenging. This comprehensive guide aims to provide you with detailed information about E45 Psoriasis Cream 50ml, including its description, directions for use, ingredients, potential side effects, and important warnings.

Psoriasis is a common skin disorder that affects millions of people in the United Kingdom. E45 Psoriasis Cream is formulated to address the specific needs of those with psoriasis by providing relief from symptoms and supporting the skin's natural healing process.


Using E45 Psoriasis Cream 50ml correctly is essential to maximize its effectiveness and ensure your safety. Here are the steps for proper application:
Clean the Affected Area: Before applying E45 Psoriasis Cream, clean the affected skin gently with mild soap and lukewarm water. Pat it dry thoroughly with a soft, clean towel.
Apply a Thin Layer: Squeeze a small amount of E45 Psoriasis Cream onto your fingertip. Apply a thin and even layer of the cream to the affected areas of the skin. Use only enough to cover the psoriasis plaques, avoiding excessive application.
Gently Rub In: Using a gentle, circular motion, massage the cream into the skin until it is fully absorbed. Ensure that the cream is evenly distributed over the affected areas.
Frequency of Application: The recommended frequency of application may vary depending on the severity of your psoriasis and your healthcare provider's instructions. In most cases, E45 Psoriasis Cream should be applied two to three times daily. Follow the guidance provided on the product packaging or by your healthcare provider.
Duration of Use: Continue using E45 Psoriasis Cream as directed by your healthcare provider or as indicated on the product packaging. Psoriasis is a chronic condition, and you may require long-term management. Do not discontinue its use prematurely, even if your symptoms improve.
Avoid Contact with Eyes and Mucous Membranes: Be cautious to prevent contact with the eyes, nose, mouth, and mucous membranes. If accidental contact occurs, rinse thoroughly with water.
Consult a Healthcare Provider: Regularly consult with your healthcare provider or dermatologist to assess your progress and determine the most appropriate treatment plan for your psoriasis.


E45 Psoriasis Cream 50ml contains a combination of active and inactive ingredients designed to address the specific needs of psoriasis-affected skin:
Active Ingredient:
Coal Tar: Coal tar is a well-established treatment for psoriasis. It helps slow down skin cell growth, reduce inflammation, and alleviate itching and scaling associated with psoriasis.
Inactive Ingredients:
The formulation may also include other inactive ingredients, such as emollients and stabilizers, to improve the texture, spreadability, and overall efficacy of the cream.

Side Effects

E45 Psoriasis Cream is generally well-tolerated, but some individuals may experience mild side effects. Common side effects may include:
Skin Irritation: Some users may experience temporary skin irritation, redness, or a burning sensation at the application site. This usually subsides as the skin adapts to the cream.
Sensitivity to Sunlight: Coal tar can make your skin more sensitive to sunlight. It's essential to apply sunscreen or protective clothing when exposed to the sun to prevent sunburn.
Skin Discoloration: Prolonged use of coal tar products may lead to skin discoloration, particularly in areas where the cream is applied. This effect is typically reversible upon discontinuation of the cream.
It's important to note that these side effects are generally mild and transient. However, if you experience severe or persistent side effects, discontinue use and consult your healthcare provider.


Before using E45 Psoriasis Cream 50ml, consider the following warnings:
Allergic Sensitivity: If you have a known allergy to any of the ingredients in E45 Psoriasis Cream, including coal tar, do not use this product, and inform your healthcare provider.
Avoid Internal Use: E45 Psoriasis Cream is for external use only. Do not ingest or apply it inside the mouth, nose, ears, or any internal body cavities.
Sun Protection: Be vigilant about protecting your skin from sunlight while using E45 Psoriasis Cream, as coal tar can increase sensitivity to UV rays. Apply sunscreen or wear protective clothing when outdoors.
Not for Long-Term Continuous Use: E45 Psoriasis Cream is generally intended for short-term use to manage psoriasis flares and symptoms. Prolonged, continuous use should be avoided without medical supervision.
Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using E45 Psoriasis Cream. While it is generally considered safe for external use, discuss its use in your specific situation.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Oct 5, 2023, 2:45 pm

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Please read our FAQs page to find out more.

Can E45 Psoriasis Cream be used on the scalp for psoriasis of the scalp?

No, E45 Psoriasis Cream is not recommended for use on the scalp. It is formulated for application to the skin and may not be suitable for the hair-covered scalp. Consider consulting your healthcare provider or dermatologist for appropriate treatments and recommendations for scalp psoriasis.

Is E45 Psoriasis Cream suitable for use on sensitive or delicate areas of the body, such as the face or genitalia?

E45 Psoriasis Cream is generally not recommended for use on the face, genitalia, or other sensitive areas of the body. These areas may require specialized treatments, and using the cream in such areas could lead to irritation. Consult with your healthcare provider for guidance on managing psoriasis in sensitive areas.

Can I apply E45 Psoriasis Cream to open psoriasis sores or bleeding skin patches?

E45 Psoriasis Cream should not be applied to open sores, bleeding skin patches, or areas with broken skin. It is intended for use on intact skin to alleviate psoriasis symptoms. If you have open sores or significant skin damage, consult your healthcare provider for appropriate wound care and psoriasis management.

How long can I safely use E45 Psoriasis Cream continuously for my psoriasis?

E45 Psoriasis Cream is generally intended for short-term use during psoriasis flares to manage symptoms. Prolonged, continuous use should be avoided without medical supervision. Consult with your healthcare provider or dermatologist to determine the most suitable long-term management plan for your psoriasis.

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