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Quick summary

Type of medicine

Oral Suspension

Works by

Alleviating pain and reducing fever

Active Ingredient


Effective within

Approximately 15 to 30 minutes



Side effects

Allergic reactions, gastrointestinal discomfort

Medication details


Calpol SixPlus Sugar Free Suspension Strawberry Flavour is a reliable and widely recognized over-the-counter medication that addresses the discomfort of pain and fever in children aged 6 years and older. Developed with utmost care and adherence to stringent safety standards, this oral suspension is a go-to solution for parents and caregivers seeking effective relief for their children. The formulation of Calpol SixPlus has been meticulously designed to provide gentle yet potent relief from mild to moderate pain and fever, commonly stemming from conditions like colds, flu, and post-immunization reactions.

The hallmark of Calpol SixPlus lies not only in its efficacy but also in its user-friendly presentation. Each box contains conveniently packaged single-use sachets, each containing 5ml of the sugar-free strawberry-flavored suspension. This thoughtful design not only ensures accurate dosing but also eliminates the need for measuring cups or spoons, simplifying the administration process.

This exceptional formulation is underpinned by the active ingredient paracetamol, a stalwart in the realm of pain relief and fever reduction. Each 5ml sachet contains 250mg of paracetamol, expertly calibrated to provide optimal relief while minimizing the risk of adverse effects. Paracetamol is widely recognized for its ability to alleviate pain and reduce fever by acting on certain areas of the brain responsible for temperature regulation and pain perception. This mode of action makes Calpol SixPlus an effective remedy for the discomfort and distress often associated with childhood illnesses.


Before administering Calpol SixPlus, ensure the child is aged 6 years or older.
Always follow the dosage instructions provided on the packaging or by a healthcare professional.
Tear open one sachet and pour the contents into a spoon or directly into the child's mouth.
The recommended dose is 5ml (one sachet) every 4 to 6 hours if needed.
Do not exceed 4 doses in 24 hours.
If symptoms persist or worsen, consult a doctor.


The active ingredient in Calpol SixPlus Sugar Free Suspension Strawberry Flavour is paracetamol. Paracetamol is a well-known pain reliever and fever reducer. Each 5ml sachet contains 250mg of paracetamol.
Other ingredients include: maltitol liquid (E965), purified water, citric acid monohydrate, sodium methylparaben (E219), sodium ethylparaben (E215), sodium propylparaben (E217), and strawberry flavour.

Side Effects

Calpol SixPlus is generally well-tolerated when used as directed. However, like any medication, there is a possibility of side effects, although not everyone will experience them. Potential side effects may include:

Allergic Reactions: Rarely, some individuals may experience allergic reactions such as skin rash, itching, swelling, or difficulty breathing. Seek medical attention if these occur.

Gastrointestinal Issues: There is a slight chance of gastrointestinal discomfort, nausea, or vomiting.

Blood Disorders: In extremely rare cases, paracetamol can affect blood cell production, leading to changes in blood cell counts.

If your child experiences any side effects or reactions not listed here, discontinue use and consult a healthcare professional.


Age and Dosage: Calpol SixPlus is intended for children aged 6 years and older. Ensure the correct dosage based on the child's age and weight. Never exceed the recommended dose.

Medical Conditions: If your child has liver or kidney problems, consult a doctor before using Calpol SixPlus.

Other Medications: Inform a healthcare professional about all other medications your child is taking, as paracetamol might interact with certain drugs.

Allergies: If your child is allergic to paracetamol or any of the other ingredients, do not use this product.

Overdose Risk: Excessive use of paracetamol can lead to serious health issues, including liver damage. Do not combine with other medications containing paracetamol.

Storage: Keep out of sight and reach of children. Store the sachets in a cool, dry place, away from direct sunlight.

Seek Medical Advice: If your child's symptoms persist for more than 3 days or worsen, consult a healthcare professional.

Medically reviewed and published

  • This page was medically reviewed by Dr Sohaib Imtiaz, Clinical Lead on Oct 11, 2023, 9:45 am

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Please read our FAQs page to find out more.

Can I use Calpol SixPlus for younger children?

Calpol SixPlus Sugar Free Suspension is specifically formulated for children aged 6 years and older. For younger children, consider using other Calpol formulations suitable for their age group.

How often can I administer Calpol SixPlus to my child?

The recommended dosage is 5ml (one sachet) every 4 to 6 hours as needed. However, do not exceed 4 doses within a 24-hour period. Always adhere to the dosing guidelines provided on the packaging or by a healthcare professional.

Can I mix Calpol SixPlus with other medications?

It's important to consult a healthcare professional before combining Calpol SixPlus with other medications. This is especially true if the child is already taking other medications or has underlying health conditions to avoid potential interactions.

What if my child doesn't like the taste of medicine?

Calpol SixPlus offers a delightful strawberry flavor to enhance palatability. However, if your child is resistant to taking the medication, consult your healthcare provider. They might provide additional guidance on administration techniques or suggest alternative options.

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